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PhD in Cellular Microbiology (2003) Centre for Molecular Microbiology and Infection, Imperial College London, UK

MSc in Infectious Diseases (1999) Hammersmith Hospital, Imperial College London, UK

Four-year undergraduate degree in Microbiology (1998) Biotechnology School, Porto Catholic University, Portugal


Salcedo SP, Marchesini MI, Degos C, Terwagne M, Von Bargen K, Lepidi H, Herrmann CK, Lacerda TLS, Imbert PRC, Pierre P, Alexopoulou L, Letesso JJ, Comerci DJ and Gorvel JP. (2013) BtpB, a novel Brucella TIR-containing effector protein with immune modulatory functions. Frontiers in Cellular and Infection Microbiology. 3 : 28.

Salcedo SP and Alexopoulou L. Investigating TLR responses in murine dendritic cells. (2013) Methods in Molecular Biology. In press

Salcedo SP, Chevrier N, Lacerda TLS, Ben Amira A, Gerart S, Gorvel VA, de Chastellier C, Blasco JM, Mege JL and Gorvel JP (2013). Pathogenic Brucellae replicate in human trophoblasts. Journal of Infectious Diseases ; 207 (7) : 1075-83.

Lacerda TLS, Salcedo SP and Gorvel JP (2013). Brucella T4SS : the VIP pass inside host cells. Current Opinion in Microbiology ; S1369-5274 (12) : 171-3.

Von Bargen K, Gorvel JP and Salcedo SP (2012). Internal affairs : investigating the Brucella intracellular lifestyle. FEMS Microbiology Reviews ; 36 (3) : 533-62.

Martirosyan A, Pérez-Gutierrez C, Banchereau R, Dutartre H, Lecine P, Dullaers M, Mello M, Salcedo SP, Muller A, Leserman L, Levy Y, Zurawski G, Zurawski S, Moreno E, Moriyón I, Klechevsky E, Banchereau J, Oh S, Gorvel JP. (2012) Brucella β 1,2 Cyclic Glucan Is an Activator of Human and Mouse Dendritic Cells. PLoS Pathogens  ; 8 (11) : e1002983. 

Marchesini MI, Herrmann CK, Salcedo SP, Gorvel JP and Comerci DJ (2011). In search of Brucella abortus Type IV secretion substrates : screening and identification of four proteins translocated into host cells through VirB system. Cellular Microbiology ; 13 (8) : 1261-74.

De Barsy M, Jamet A, Filopon D, Nicolas C, Laloux G, Rual JF, Muller A, Twizere JC, Nikegfac B, Vandenhaute J, Hill DE, Salcedo SP, Gorvel JP, Letesson JJ and de Bolle X (2011). Identification of a Brucella spp. Secreted Effector Specifically Interacting with Human Small GTPase Rab2. Cellular Microbiology ; 13 (7) : 1044-58.

Salcedo SP and Cid VJ (2011). Nontypable Haemophilus influenzae : an intracellular phase within epithelial cells might contribute to persistence. Comment in Microbiology ; 157 : 1 - 2.

Amara AB, Ghigo E, Le Priol E, Le´polard C, Salcedo SP, Lemichez E, Bretelle F, Capo C, Mege JL (2010). Coxiella burnetii, the Agent of Q Fever, Replicates within Trophoblasts and Induces a Unique Transcriptional. PlosOne, vol5, e15315.

Archambaud C, Salcedo SP, Lelouard H, Devilard E, de Bovis B, Van Rooijen N, Gorvel JP and Malissen B (2010) Contrasted role of macrophages and dendritic cells in controlling initial pulmonary Brucella infection. European Journal of Immunology. 40 (12) : 3458-71.

Lacerda TL, Cardoso PG, Augusto de Almeida L, Camargo IL, Afonso DA, Trant CC, Macedo GC, Campos E, Cravero SL, Salcedo SP, Gorvel JP, Oliveira SC (2010). Inactivation of formyltransferase (wbkC) gene generates a Brucella abortus rough strain that is attenuated in macrophages and in mice. Vaccine. (34):5627-34.

Trant CGMC, Lacerda TLS, Azevedo V, Rosinha GMS, Salcedo SP, Gorvel JP, Oliveira SC (2010). Brucella abortus phosphoglycerate kinase mutant is highly attenuated and induces superior protection than vaccine strain 19 in IRF-1 knockout and 129/Sv mice. Infection and Immunity 78 (5) : 2283-91.

Fugier E, Salcedo SP, Chastellier C, Pophillat M, Muller A, Arce-Gorvel V, Fourquet P, and Gorvel JP (2009) The glyceraldehyde-3-phosphate dehydrogenase and the small GTPase Rab 2 are crucial for Brucella replication. PLoS Pathogens 5 (6) : e1000487.

Salcedo SP, Marchesini MI, Lelouard H, Fugier E, Jolly G, Balor S, Muller A, Lapaque N, Demaria O, Alexopoulou L, Comerci DJ, Ugalde RA, Pierre P, Gorvel JP (2008) Brucella control of dendritic cell maturation is dependent on the TIR-containing protein Btp1. PLoS Pathogens 4 (2) : e21.

Deiwick J*, Salcedo SP*, Boucrot E, Gilliland SM, Henry T, Petermann N, Waterman SR, Gorvel JP, Holden DW, Meresse S. (2006) The translocated Salmonella effector proteins SseF and SseG interact and are required to establish an intracellular replication niche. Infection and Immunity 74 : 6965-72. *authors contributed equally to this work

Conde-Alvarez R, Grilló MJ, Salcedo SP, Miguel MJ, Fugier E, Gorvel JP, Moriyón I and Iriarte M (2006) Synthesis of phosphatidylcholine, a typical eukaryoyic phospholipid, is necessary for full virulence of the intracellular bacterial parasite Brucella abortus. Cellular Microbiology 8 : 1322-35.

Arellano-Reynoso B, Lapaque N, Salcedo S, Briones G, Ciocchini AE, Ugalde R, Moreno E, Moriyon I, Gorvel JP (2005) Cyclic beta-1,2-glucan is a Brucella virulence factor required for intracellular survival. Nature Immunology. 6 : 618-25.

Celli J, Salcedo SP and Gorvel JP (2005) Brucella coopts the small GTPase Sar1 for intracellular replication PNAS 102 : 1673-1679.

Salcedo SP and Holden DW. (2003) SseG, a virulence protein that targets Salmonella to the Golgi network. EMBO Journal 22 : 5003-5014.

Beuzón CR, Salcedo SP and Holden DW. (2002) Growth and killing of a Salmonella enterica serovar Typhimurium sifA mutant strain in the cytosol of different host cell lines. Microbiology 148 : 2705-2715.

Salcedo SP, Noursadeghi M, Cohen J and Holden DW. (2001) Intracellular replication of Salmonella typhimurium strains in specific subsets of splenic macrophages in vivo. Cellular Microbiology 3 : 587-597.

Reviews and book chapters

Von Bargen K, Gorvel JP and Salcedo SP (2012). Internal affairs : investigating the Brucella intracellular lifestyle. FEMS Microbiology Reviews ; 36 (3) : 533-62.

Salcedo SP and Gorvel JP (2009). Brucella, a perfect Trojan horse in phagocytes. 427-435 in Phagocyte-Pathogen interactions. Editors : Russell DG and Gordon S. ASM Press.

Roy CR, Salcedo SP and Gorvel JP (2006) Pathogen–endoplasmic-reticulum interactions : in through the out door. Nature Reviews Immunology 6 : 136-47.

Salcedo SP and Holden DW. (2005) Bacterial interactions with the secretory pathway. Current Opinion in Microbiology 8 : 92-98.