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Accueil du site > Équipes > Biocristallographie et Biologie Structurale des Cibles Thérapeutiques (N Aghajari) > Publications

Publications

[2013] [2012] [2011] [2010
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[1999] [1998] [1997] [1996

2013 [Top] 8
136.  The acid tolerant and cold-active ?-galactosidase from Lactococcus lactis strain is an attractive biocatalyst for lactose hydrolysis.   
Vincent V, Aghajari N, Pollet N, Boisson A, Boudebbouze S, Haser R, Maguin E, Rhimi M
(2013) Antonie Van Leeuwenhoek 103 : 701-12

135.  In vitro functional analyses of the human immunodeficiency virus type 1 (HIV-1) integrase mutants give new insights into the intasome assembly.   
Cellier C, Moreau K, Gallay K, Ballandras A, Gouet P, Ronfort C
(2013) Virology 439 : 97-104

134.  Identification of critical residues for the activity and thermostability of Streptomyces sp. SK glucose isomerase.   
Ben Hlima H, Bejar S, Riguet J, Haser R, Aghajari N
(2013) Appl Microbiol Biotechnol 

133.  Mutations inducing an active-site aperture in Rhizobium sp. sucrose isomerase confer hydrolytic activity.   
Lipski A, Watzlawick H, Ravaud S, Robert X, Rhimi M, Haser R, Mattes R, Aghajari N
(2013) Acta Crystallogr D Biol Crystallogr 69 : 298-307

132.  Mapping of heparin/heparan sulfate binding sites on ?v?3 integrin by molecular docking.   
Ballut L, Sapay N, Chautard E, Imberty A, Ricard-Blum S
(2013) J Mol Recognit 26 : 76-85

131.  Identification and characterization of inhibitors of cytoplasmic 5'-nucleotidase cN-II issued from virtual screening.   
Jordheim LP, Marton Z, Rhimi M, Cros-Perrial E, Lionne C, Peyrottes S, Dumontet C, Aghajari N, Chaloin L
(2013) Biochem Pharmacol 85 : 497-506

130.  PelN Is a New Pectate Lyase of Dickeya dadantii with Unusual Characteristics.   
Hassan S, Shevchik VE, Robert X, Hugouvieux-Cotte-Pattat N
(2013) J Bacteriol 195 : 2197-206

129.  Biophysical characterization of the feline immunodeficiency virus p24 capsid protein conformation and in vitro capsid assembly.   
Serriere J, Fenel D, Schoehn G, Gouet P, Guillon C
(2013) PLoS One 8 : e56424-e56424

2012 [Top] 8
128.  Mutational dissection of the S/T-kinase StkP reveals crucial roles in cell division of Streptococcus pneumoniae.   
Fleurie A, Cluzel C, Guiral S, Freton C, Galisson F, Zanella-Cleon I, Di Guilmi AM, Grangeasse C
(2012) Mol Microbiol 83 : 746-58

127.  Structural basis of fibrillar collagen trimerization and related genetic disorders.   
Bourhis JM, Mariano N, Zhao Y, Harlos K, Exposito JY, Jones EY, Moali C, Aghajari N, Hulmes DJ
(2012) Nat Struct Mol Biol 19 : 1031-6

126.  Engineered glucose isomerase from Streptomyces sp. SK is resistant to Ca²? inhibition and Co²? independent.   
Hlima HB, Aghajari N, Ali MB, Haser R, Bejar S
(2012) J Ind Microbiol Biotechnol 39 : 537-46

125.  The overexpression of the SAPB of Bacillus pumilus CBS and mutated sapB-L31I/T33S/N99Y alkaline proteases in Bacillus subtilis DB430: new attractive properties for the mutant enzyme.   
Jaouadi NZ, Jaouadi B, Aghajari N, Bejar S
(2012) Bioresour Technol 105 : 142-51

124.  Production and crystallization of the C-propeptide trimer from human procollagen III.   
Bourhis JM, Mariano N, Zhao Y, Walter TS, El Omari K, Delolme F, Moali C, Hulmes DJ, Aghajari N
(2012) Acta Crystallogr Sect F Struct Biol Cryst Commun 68 : 1209-13

123.  Blocking human enterovirus 71 replication by targeting viral 2A protease.   
Falah N, Montserret R, Lelogeais V, Schuffenecker I, Lina B, Cortay JC, Violot S
(2012) J Antimicrob Chemother 67 : 2865-9

122.  Ex vivo and in vivo inhibition of human rhinovirus replication by a new pseudosubstrate of viral 2A protease.   
Falah N, Violot S, Decimo D, Berri F, Foucault-Grunenwald ML, Ohlmann T, Schuffenecker I, Morfin F, Lina B, Riteau B, Cortay JC
(2012) J Virol 86 : 691-704

121.  The molecular mechanism of thermostable ?-galactosidases AgaA and AgaB explained by x-ray crystallography and mutational studies.   
Merceron R, Foucault M, Haser R, Mattes R, Watzlawick H, Gouet P
(2012) J Biol Chem 287 : 39642-52

2011 [Top] 14
120.  Structuring detergents for extracting and stabilizing functional membrane proteins.     
Matar-Merheb R, Rhimi M, Leydier A, Huche F, Galian C, Desuzinges-Mandon E, Ficheux D, Flot D, Aghajari N, Kahn R, Di Pietro A, Jault JM, Coleman AW, Falson P
(2011) PLoS One 6 : e18036-e18036

119.  Toward the smallest active subdomain of a TIM-barrel fold: insights from a truncated ?-amylase.   
Ben Ali M, Ghram M, Hmani H, Khemakhem B, Haser R, Bejar S
(2011) Biochem Biophys Res Commun 411 : 265-70

118.  A novel proteomics approach to identify SUMOylated proteins and their modification sites in human cells.   
Galisson F, Mahrouche L, Courcelles M, Bonneil E, Meloche S, Chelbi-Alix MK, Thibault P
(2011) Mol Cell Proteomics 10

117.  Functional analyses of mutants of the central core domain of an Avian Sarcoma/Leukemia Virus integrase.   
Charmetant J, Moreau K, Gallay K, Ballandras A, Gouet P, Ronfort C
(2011) Virology 421 : 42-50

116.  The acid-tolerant L-arabinose isomerase from the mesophilic Shewanella sp. ANA-3 is highly active at low temperatures.   
Rhimi M, Bajic G, Ilhammami R, Boudebbouze S, Maguin E, Haser R, Aghajari N
(2011) Microb Cell Fact 10 : 96-96

115.  Matricryptins derived from collagens and proteoglycans.     
Ricard-Blum S, Ballut L
(2011) Front Biosci 16 : 674-97

114.  Surface characterization and efficiency of a matrix-free and flat carboxylated gold sensor chip for surface plasmon resonance (SPR).   
Roussille L, Brotons G, Ballut L, Louarn G, Ausserre D, Ricard-Blum S
(2011) Anal Bioanal Chem 401 : 1601-17

113.  MatrixDB, the extracellular matrix interaction database.     
Chautard E, Fatoux-Ardore M, Ballut L, Thierry-Mieg N, Ricard-Blum S
(2011) Nucleic Acids Res 39 : D235-40

112.  Enhancement of the thermostability of the maltogenic amylase MAUS149 by Gly312Ala and Lys436Arg substitutions.     
Ben Mabrouk S, Aghajari N, Ben Ali M, Ben Messaoud E, Juy M, Haser R, Bejar S
(2011) Bioresour Technol 102 : 1740-6

111.  A Novel Proteomics Approach to Identify SUMOylated Proteins and Their Modification Sites in Human Cells     
Galisson F, Mahrouche L, Courcelles M, Bonneil E, Meloche S, Chelbi-Alix MK, Thibault P,
(2011) MOLECULAR & CELLULAR PROTEOMICS 10 : -

110.  Production of D-tagatose, a low caloric sweetener during milk fermentation using L-arabinose isomerase     
Rhimi M, Chouayekh H, Gouillouard I, Maguin E, Bejar S
(2011) BIORESOURCE TECHNOLOGY 102 : 3309-3315

109.  Fab'-induced folding of antigenic N-terminal peptides from intrinsically disordered HIV-1 Tat revealed by X-ray crystallography.     
Serriere J, Dugua JM, Bossus M, Verrier B, Haser R, Gouet P, Guillon C
(2011) J Mol Biol 405 : 33-42

108.  Supramolecular stabilization of acid tolerant L-arabinose isomerase from Lactobacillus sakei.   
Jebors S, Tauran Y, Aghajari N, Boudebbouze S, Maguin E, Haser R, Coleman AW, Rhimi M
(2011) Chem Commun (Camb) 47 : 12307-9

107.  A crystal structure of the catalytic core domain of an avian sarcoma and leukemia virus integrase suggests an alternate dimeric assembly.   
Ballandras A, Moreau K, Robert X, Confort MP, Merceron R, Haser R, Ronfort C, Gouet P
(2011) PLoS One 6 : e23032-e23032

2010 [Top] 6
106.  The acid tolerant L-arabinose isomerase from the food grade Lactobacillus sakei 23K is an attractive D-tagatose producer.     
Rhimi M, Ilhammami R, Bajic G, Boudebbouze S, Maguin E, Haser R, Aghajari N
(2010) Bioresour Technol 101 : 9171-7

105.  UV and X-ray structural studies of a 101-residue long Tat protein from a HIV-1 primary isolate and of its mutated, detoxified, vaccine candidate.     
Foucault M, Mayol K, Receveur-Brechot V, Bussat MC, Klinguer-Hamour C, Verrier B, Beck A, Haser R, Gouet P, Guillon C
(2010) Proteins 78 : 1441-56

104.  The extended conformation of the 2.9-A crystal structure of the three-PASTA domain of a Ser/Thr kinase from the human pathogen Staphylococcus aureus.   
Paracuellos P, Ballandras A, Robert X, Kahn R, Herve M, Mengin-Lecreulx D, Cozzone AJ, Duclos B, Gouet P
(2010) J Mol Biol 404 : 847-58

103.  Enhancement of the thermostability and the catalytic efficiency of Bacillus pumilus CBS protease by site-directed mutagenesis.     
Jaouadi B, Aghajari N, Haser R, Bejar S
(2010) Biochimie 92 : 360-9

102.  Efficient bioconversion of lactose in milk and whey: immobilization and biochemical characterization of a beta-galactosidase from the dairy Streptococcus thermophilus LMD9 strain.     
Rhimi M, Boisson A, Dejob M, Boudebouze S, Maguin E, Haser R, Aghajari N
(2010) Res Microbiol 161 : 515-25

101.  Transglutaminase-2: a new endostatin partner in the extracellular matrix of endothelial cells.     
Faye C, Inforzato A, Bignon M, Hartmann DJ, Muller L, Ballut L, Olsen BR, Day AJ, Ricard-Blum S
(2010) Biochem J 427 : 467-75

2009 [Top] 14
100.  C-terminal residues regulate localization and function of the antiapoptotic protein Bfl-1.     
Brien G, Debaud AL, Robert X, Oliver L, Trescol-Biemont MC, Cauquil N, Geneste O, Aghajari N, Vallette FM, Haser R, Bonnefoy-Berard N
(2009) J Biol Chem 284 : 30257-63

99.  Exploring the acidotolerance of beta-galactosidase from Lactobacillus delbrueckii subsp. bulgaricus: an attractive enzyme for lactose bioconversion.     
Rhimi M, Aghajari N, Jaouadi B, Juy M, Boudebbouze S, Maguin E, Haser R, Bejar S
(2009) Res Microbiol 160 : 775-84

98.  Structural basis of X-ray-induced transient photobleaching in a photoactivatable green fluorescent protein.     
Adam V, Carpentier P, Violot S, Lelimousin M, Darnault C, Nienhaus GU, Bourgeois D
(2009) J Am Chem Soc 131 : 18063-5

97.  MatrixDB, a database focused on extracellular protein-protein and protein-carbohydrate interactions.     
Chautard E, Ballut L, Thierry-Mieg N, Ricard-Blum S
(2009) Bioinformatics 25 : 690-1

96.  The importance of an extra loop in the B-domain of an alpha-amylase from B. stearothermophilus US100.     
Khemakhem B, Ben Ali M, Aghajari N, Juy M, Haser R, Bejar S
(2009) Biochem Biophys Res Commun 385 : 78-83

95.  Verdoheme formation in Proteus mirabilis catalase.   
Andreoletti P, Mouesca JM, Gouet P, Jaquinod M, Capeillere-Blandin C, Jouve HM
(2009) Biochim Biophys Acta 1790 : 741-53

94.  Rational design of Bacillus stearothermophilus US100 L-arabinose isomerase: potential applications for D-tagatose production.     
Rhimi M, Aghajari N, Juy M, Chouayekh H, Maguin E, Haser R, Bejar S
(2009) Biochimie 91 : 650-3

93.  Verdoheme formation in Proteus mirabilis catalase     
Andreoletti P, Mouesca JM, Gouet P, Jaquinod M, Capeillere-Blandin C, Jouve HM,
(2009) BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1790 : 741-753

92.  Reverse pH-dependence of chromophore protonation explains the large Stokes shift of the red fluorescent protein mKeima.     
Violot S, Carpentier P, Blanchoin L, Bourgeois D
(2009) J Am Chem Soc 131 : 10356-7

91.  Crystallization and initial X-ray diffraction study of the three PASTA domains of the Ser/Thr kinase Stk1 from the human pathogen Staphylococcus aureus.     
Paracuellos P, Ballandras A, Robert X, Cozzone AJ, Duclos B, Gouet P
(2009) Acta Crystallogr Sect F Struct Biol Cryst Commun 65 : 1187-9

90.  Structural basis for the phototoxicity of the fluorescent protein KillerRed.     
Carpentier P, Violot S, Blanchoin L, Bourgeois D
(2009) FEBS Lett 583 : 2839-42

89.  Structural determinants of product specificity of sucrose isomerases.     
Ravaud S, Robert X, Watzlawick H, Haser R, Mattes R, Aghajari N
(2009) FEBS Lett 583 : 1964-8

88.  Involvement of cysteine 306 and alanine 63 in the thermostability and oligomeric organization of glucose isomerase from Streptomyces sp SK     
Borgi MA, Rhimi M, Aghajari N, Ben Ali M, Juy M, Haser R, Bejar S
(2009) BIOLOGIA 64 : 845-851

87.  Engineering of the alpha-amylase from Geobacillus stearothermophilus US100 for detergent incorporation.     
Khemakhem B, Ali MB, Aghajari N, Juy M, Haser R, Bejar S
(2009) Biotechnol Bioeng 102 : 380-9

2008 [Top] 11
86.  Insights into sucrose isomerization from crystal structures of the Pseudomonas mesoacidophila MX-45 sucrose isomerase, MutB     
Ravaud S, Robert X, Watzlawick H, Laurent S, Haser R, Mattes R, Aghajari N
(2008) BIOCATALYSIS AND BIOTRANSFORMATION 26 : 111-119

85.  Structures of mutants of cellulase Ce148F of Clostridium cellulolyticum in complex with long hemithiocellooligosaccharides give rise to a new view of the substrate pathway during processive action     
Parsiegla G, Reverbel C, Tardif C, Driguez H, Haser R
(2008) JOURNAL OF MOLECULAR BIOLOGY 375 : 499-510

84.  Crystallization and X-ray analysis of the Schistosoma mansoni guanidino kinase.     
Awama AM, Paracuellos P, Laurent S, Dissous C, Marcillat O, Gouet P
(2008) Acta Crystallogr Sect F Struct Biol Cryst Commun 64 : 854-7

83.  Biochemical and molecular characterization of a detergent-stable serine alkaline protease from Bacillus pumilus CBS with high catalytic efficiency     
Jaouadi B , Ellouz-Chaabouni S , Rhimi M , Bejar S
(2008) BIOCHIMIE 90 : 1291-1305

82.  Bacterial sucrose isomerases: properties and structural studies     
Rhimi M, Haser R, Aghajari N
(2008) BIOLOGIA 63 : 1020-1027

81.  NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity.   
Chamieh H, Ballut L, Bonneau F, Le Hir H
(2008) Nat Struct Mol Biol 15 : 85-93

80.  Multi-site substrate binding and interplay in barley alpha-amylase 1.     
Nielsen MM, Seo ES, Bozonnet S, Aghajari N, Robert X, Haser R, Svensson B
(2008) FEBS Lett 582 : 2567-71

79.  An enzyme family reunion - similarities, differences and eccentricities in actions on alpha-glucans     
Seo ES, Christiansen C, Hachem MA, Nielsen MM, Fukuda K, Bozonnet S, Blennow A, Aghajari N, Haser R, Svensson B
(2008) BIOLOGIA 63 : 967-979

78.  Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed beta-propeller domain of the HIV-1 cellular interactor EED.     
Rakotobe D, Violot S, Hong SS, Gouet P, Boulanger P
(2008) Virol J 5 : 32-32

77.  The crystal structure of pectate lyase peli from soft rot pathogen Erwinia chrysanthemi in complex with its substrate.     
Creze C, Castang S, Derivery E, Haser R, Hugouvieux-Cotte-Pattat N, Shevchik VE, Gouet P
(2008) J Biol Chem 283 : 18260-8

76.  Roles of multiple surface sites, long substrate binding clefts, and carbohydrate binding modules in the action of amylolytic enzymes on polysaccharide substrates     
Nielsen MM, Seo ES, Dilokpimol A, Andersen J, Abou Hachem M, Naested H, Willemoes M, Bozonnet S, Kandra L, Gyemant G, Haser R, Aghajari N, Svensson B
(2008) BIOCATALYSIS AND BIOTRANSFORMATION 26 : 59-67

2007 [Top] 10
75.  The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity.     
Bozonnet S, Jensen MT, Nielsen MM, Aghajari N, Jensen MH, Kramhøft B, Willemoes M, Tranier S, Haser R, Svensson B
(2007) FEBS J 274 : 5055-67

74.  Several enzymes of the central metabolism are phosphorylated in Staphylococcus aureus.     
Lomas-Lopez R, Paracuellos P, Riberty M, Cozzone AJ, Duclos B
(2007) FEMS Microbiol Lett 272 : 35-42

73.  Formulation of HIV-1 Tat and p24 antigens by PLA nanoparticles or MF59 impacts the breadth, but not the magnitude, of serum and faecal antibody responses in rabbits.     
Guillon C, Mayol K, Terrat C, Compagnon C, Primard C, Charles MH, Delair T, Munier S, Verrier B
(2007) Vaccine 25 : 7491-501

72.  Design and characterization of an HIV-1 Tat mutant: inactivation of viral and cellular functions but not antigenicity.     
Mayol K, Munier S, Beck A, Verrier B, Guillon C
(2007) Vaccine 25 : 6047-60

71.  Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization.     
Ravaud S, Robert X, Watzlawick H, Haser R, Mattes R, Aghajari N
(2007) J Biol Chem 282 : 28126-36

70.  Structure of a d(TGGGGT) quadruplex crystallized in the presence of Li+ ions.     
Creze C, Rinaldi B, Haser R, Bouvet P, Gouet P
(2007) Acta Crystallogr D Biol Crystallogr 63 : 682-8

69.  Probing the essential catalytic residues and substrate affinity in the thermoactive Bacillus stearothermophilus US100 L-arabinose isomerase by site-directed mutagenesis.     
Rhimi M, Juy M, Aghajari N, Haser R, Bejar S
(2007) J Bacteriol 189 : 3556-63

68.  Elastic properties of viruses.     
Stephanidis B, Adichtchev S, Gouet P, McPherson A, Mermet A
(2007) Biophys J 93 : 1354-9

67.  Tyrosine-kinase Wzc from Escherichia coli possesses an ATPase activity regulated by autophosphorylation.     
Soulat D, Jault JM, Geourjon C, Gouet P, Cozzone AJ, Grangeasse C
(2007) FEMS Microbiol Lett 274 : 252-9

66.  The linker region plays a key role in the adaptation to cold of the cellulase from an Antarctic bacterium.     
Sonan GK, Receveur-Brechot V, Duez C, Aghajari N, Czjzek M, Haser R, Gerday C
(2007) Biochem J 407 : 293-302

2006 [Top] 8
65.  Interactions of barley alpha-amylase isozymes with Ca2+, substrates and proteinaceous inhibitors      
Abou Hachem M, Bozonnet S, Willemoes M, Kramhoft B, Fukuda K, Bonsager BC, Jensen MT, Nohr J, Tranier S, Juge N, Robert X, Haser R, Aghajari N, Svensson B
(2006) BIOCATALYSIS AND BIOTRANSFORMATION  24 : 83-93

64.  Insights into early extracellular matrix evolution: spongin short chain collagen-related proteins are homologous to basement membrane type IV collagens and form a novel family widely distributed in invertebrates.     
Aouacheria A, Geourjon C, Aghajari N, Navratil V, Deleage G, Lethias C, Exposito JY
(2006) Mol Biol Evol 23 : 2288-302

63.  Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA     
Andersen CBF , Ballut L , Johansen JS , Chamieh H , Nielsen KH , Oliveira CLP , Pedersen JS , Seraphin B , Le Hir H , Andersen GR
(2006) SCIENCE 313 : 1968-1972

62.  Crystallization and preliminary X-ray diffraction studies of two thermostable alpha-galactosidases from glycoside hydrolase family 36.     
Foucault M, Watzlawick H, Mattes R, Haser R, Gouet P
(2006) Acta Crystallogr Sect F Struct Biol Cryst Commun 62 : 100-3

61.  The ABC transporter BmrA from Bacillus subtilis is a functional dimer when in a detergent-solubilized state.     
Ravaud S, Do Cao MA, Jidenko M, Ebel C, Le Maire M, Jault JM, Di Pietro A, Haser R, Aghajari N
(2006) Biochem J 395 : 345-53

60.  Overexpression, purification, crystallization and preliminary diffraction studies of the Protaminobacter rubrum sucrose isomerase SmuA.     
Ravaud S, Watzlawick H, Haser R, Mattes R, Aghajari N
(2006) Acta Crystallogr Sect F Struct Biol Cryst Commun 62 : 74-6

59.  Thermostability enhancement and change in starch hydrolysis profile of the maltohexaose-forming amylase of Bacillus stearothermophilus US100 strain.     
Ben Ali M, Khemakhem B, Robert X, Haser R, Bejar S
(2006) Biochem J 394 : 51-6

58.  Direct evidence for the modulation of the activity of the Erwinia chrysanthemi quorum-sensing regulator ExpR by acylhomoserine lactone pheromone.     
Castang S, Reverchon S, Gouet P, Nasser W
(2006) J Biol Chem 281 : 29972-87

2005 [Top] 9
57.  Towards the three-dimensional structure of a sucrose isomerase from Pseudomonas mesoacidophila MX-45      
Ravaud S, Watzlawick H, Mattes R, Haser R, Aghajari N
(2005) BIOLOGIA  60 : 89-95

56.  Water-protein hydrogen exchange in the micro-crystalline protein crh as observed by solid state NMR spectroscopy.     
Bockmann A, Juy M, Bettler E, Emsley L, Galinier A, Penin F, Lesage A
(2005) J Biomol NMR 32 : 195-207

55.  Binding of carbohydrates and protein inhibitors to the surface of alpha-amylases      
Bozonnet S, Bonsager BC, Kramhoft B, Mori H, Hachem MA, Willemoes M, Jensen MT, Fukuda K, Nielsen PK, Juge N, Aghajari N, Tranier S, Robert X, Haser R, Svensson B
(2005) BIOLOGIA  60 : 27-36

54.  Structure of a full length psychrophilic cellulase from Pseudoalteromonas haloplanktis revealed by X-ray diffraction and small angle X-ray scattering.     
Violot S, Aghajari N, Czjzek M, Feller G, Sonan GK, Gouet P, Gerday C, Haser R, Receveur-Brechot V
(2005) J Mol Biol 348 : 1211-24

53.  Biased mutagenesis in the N-terminal region by degenerate oligonucleotide gene shuffling enhances secretory expression of barley alpha-amylase 2 in yeast.     
Fukuda K, Jensen MH, Haser R, Aghajari N, Svensson B
(2005) Protein Eng Des Sel 18 : 515-26

52.  Oligosaccharide binding to barley alpha-amylase 1.     
Robert X, Haser R, Mori H, Svensson B, Aghajari N
(2005) J Biol Chem 280 : 32968-78

51.  Insights into the "pair of sugar tongs" surface binding site in barley alpha-amylase isozymes and crystallization of appropriate sugar tongs mutants      
Tranier S, Deville K, Robert X, Bozonnet S, Haser R, Svensson B, Aghajari N
(2005) BIOLOGIA  60 : 37-46

50.  Cooperative effect of two surface amino acid mutations (Q252L and E170K) in glucose dehydrogenase from Bacillus megaterium IWG3 on stabilization of its oligomeric state.     
Baik SH, Michel F, Aghajari N, Haser R, Harayama S
(2005) Appl Environ Microbiol 71 : 3285-93

49.  Expression, purification, crystallization and preliminary X-ray crystallographic studies of the trehalulose synthase MutB from Pseudomonas mesoacidophila MX-45.     
Ravaud S, Watzlawick H, Haser R, Mattes R, Aghajari N
(2005) Acta Crystallogr Sect F Struct Biol Cryst Commun 61 : 100-3

2004 [Top] 4
48.  Mutational analyses of the core domain of Avian Leukemia and Sarcoma Viruses integrase: critical residues for concerted integration and multimerization.     
Moreau K, Faure C, Violot S, Gouet P, Verdier G, Ronfort C
(2004) Virology 318 : 566-81

47.  N-Sulfonyl homoserine lactones as antagonists of bacterial quorum sensing.     
Castang S, Chantegrel B, Deshayes C, Dolmazon R, Gouet P, Haser R, Reverchon S, Nasser W, Hugouvieux-Cotte-Pattat N, Doutheau A
(2004) Bioorg Med Chem Lett 14 : 5145-9

46.  Crystallization of the pectate lyase PelI from Erwinia chrysanthemi and SAD phasing of a gold derivative.     
Castang S, Shevchik VE, Hugouvieux-Cotte-Pattat N, Legrand P, Haser R, Gouet P
(2004) Acta Crystallogr D Biol Crystallogr 60 : 190-2

45.  Glucose isomerase of the Streptomyces sp. SK strain: purification, sequence analysis and implication of alanine 103 residue in the enzyme thermostability and acidotolerance.     
Borgi MA, Srih-Belguith K, Ben Ali M, Mezghani M, Tranier S, Haser R, Bejar S
(2004) Biochimie 86 : 561-8

2003 [Top] 9
44.  X-Ray crystal structure of the multidomain endoglucanase Cel9G from Clostridium cellulolyticum complexed with natural and synthetic cello-oligosaccharides.     
Mandelman D, Belaich A, Belaich JP, Aghajari N, Driguez H, Haser R
(2003) J Bacteriol 185 : 4127-35

43.  Solid state NMR sequential resonance assignments and conformational analysis of the 2x10.4 kDa dimeric form of the Bacillus subtilis protein Crh.     
Bockmann A, Lange A, Galinier A, Luca S, Giraud N, Juy M, Heise H, Montserret R, Penin F, Baldus M
(2003) J Biomol NMR 27 : 323-39

42.  Dimerization of Crh by reversible 3D domain swapping induces structural adjustments to its monomeric homologue Hpr.     
Juy M, Penin F, Favier A, Galinier A, Montserret R, Haser R, Deutscher J, Bockmann A
(2003) J Mol Biol 332 : 767-76

41.  Expression, purification, crystallization and preliminary X-ray crystallographic studies of a psychrophilic cellulase from Pseudoalteromonas haloplanktis.     
Violot S, Haser R, Sonan G, Georlette D, Feller G, Aghajari N
(2003) Acta Crystallogr D Biol Crystallogr 59 : 1256-8

40.  ESPript/ENDscript: Extracting and rendering sequence and 3D information from atomic structures of proteins.     
Gouet P, Robert X, Courcelle E
(2003) Nucleic Acids Res 31 : 3320-3

39.  Probing the role of divalent metal ions in a bacterial psychrophilic metalloprotease: binding studies of an enzyme in the crystalline state by x-ray crystallography.     
Ravaud S, Gouet P, Haser R, Aghajari N
(2003) J Bacteriol 185 : 4195-203

38.  The structure of barley alpha-amylase isozyme 1 reveals a novel role of domain C in substrate recognition and binding: a pair of sugar tongs.     
Robert X, Haser R, Gottschalk TE, Ratajczak F, Driguez H, Svensson B, Aghajari N
(2003) Structure 11 : 973-84

37.  Structural studies of Proteus mirabilis catalase in its ground state, oxidized state and in complex with formic acid.     
Andreoletti P, Pernoud A, Sainz G, Gouet P, Jouve HM
(2003) Acta Crystallogr D Biol Crystallogr 59 : 2163-8

36.  Crystal structures of a psychrophilic metalloprotease reveal new insights into catalysis by cold-adapted proteases.     
Aghajari N, Van Petegem F, Villeret V, Chessa JP, Gerday C, Haser R, Van Beeumen J
(2003) Proteins 50 : 636-47

2002 [Top] 8
35.  Cel9M, a new family 9 cellulase of the Clostridium cellulolyticum cellulosome.     
Belaich A, Parsiegla G, Gal L, Villard C, Haser R, Belaich JP
(2002) J Bacteriol 184 : 1378-84

34.  Crystallographic evidence of a transglycosylation reaction: ternary complexes of a psychrophilic alpha-amylase.     
Aghajari N, Roth M, Haser R
(2002) Biochemistry 41 : 4273-80

33.  Expression, purification and preliminary crystallographic studies of alpha-amylase isozyme 1 from barley seeds.     
Robert X, Gottschalk TE, Haser R, Svensson B, Aghajari N
(2002) Acta Crystallogr D Biol Crystallogr 58 : 683-6

32.  Crystallization and preliminary X-ray study of an N-terminal fragment of rat liver ribosomal P2 protein.     
Mandelman D, Gonzalo P, Lavergne JP, Corbier C, Reboud JP, Haser R
(2002) Acta Crystallogr D Biol Crystallogr 58 : 668-71

31.  Structural basis of alpha-amylase activation by chloride.     
Aghajari N, Feller G, Gerday C, Haser R
(2002) Protein Sci 11 : 1435-41

30.  Crystal structure of the cellulase Cel9M enlightens structure/function relationships of the variable catalytic modules in glycoside hydrolases.     
Parsiegla G, Belaich A, Belaich JP, Haser R
(2002) Biochemistry 41 : 11134-42

29.  Comparison of crystal structures of barley alpha-amylase 1 and 2: implications for isozyme differences in stability and activity      
Robert X, Haser R, Svensson B, Aghajari N
(2002) BIOLOGIA  57 : 59-70

28.  ENDscript: a workflow to display sequence and structure information.     
Gouet P, Courcelle E
(2002) Bioinformatics 18 : 767-8

2001 [Top] 6
27.  Structure of cytochrome c7 from Desulfuromonas acetoxidans at 1.9 A resolution.     
Czjzek M, Arnoux P, Haser R, Shepard W
(2001) Acta Crystallogr D Biol Crystallogr 57 : 670-8

26.  Crystallization and preliminary X-ray analysis of a bacterial psychrophilic enzyme, phosphoglycerate kinase.     
Mandelman D, Bentahir M, Feller G, Gerday C, Haser R
(2001) Acta Crystallogr D Biol Crystallogr 57 : 1666-8

25.  Specificity modulation of barley alpha-amylase through biased random mutagenesis involving a conserved tripeptide in beta --> alpha loop 7 of the catalytic (beta/alpha)(8)-barrel domain.     
Gottschalk TE, Tull D, Aghajari N, Haser R, Svensson B
(2001) Biochemistry 40 : 12844-54

24.  Type II protein secretion in gram-negative pathogenic bacteria: the study of the structure/secretion relationships of the cellulase Cel5 (formerly EGZ) from Erwinia chrysanthemi.     
Chapon V, Czjzek M, El Hassouni M, Py B, Juy M, Barras F
(2001) J Mol Biol 310 : 1055-66

23.  Translocation portals for the substrates and products of a viral transcription complex: the bluetongue virus core.     
Diprose JM, Burroughs JN, Sutton GC, Goldsmith A, Gouet P, Malby R, Overton I, Zientara S, Mertens PP, Stuart DI, Grimes JM
(2001) EMBO J 20 : 7229-39

22.  Further insights into the mechanism of function of the response regulator CheY from crystallographic studies of the CheY--CheA(124--257) complex.     
Gouet P, Chinardet N, Welch M, Guillet V, Cabantous S, Birck C, Mourey L, Samama JP
(2001) Acta Crystallogr D Biol Crystallogr 57 : 44-51

2000 [Top] 4
21.  Specific inhibition of barley alpha-amylase 2 by barley alpha-amylase/subtilisin inhibitor depends on charge interactions and can be conferred to isozyme 1 by mutation.     
Rodenburg KW, Vallee F, Juge N, Aghajari N, Guo X, Haser R, Svensson B
(2000) Eur J Biochem 267 : 1019-29

20.  Relationship between exopolysaccharide production and protein-tyrosine phosphorylation in gram-negative bacteria.     
Vincent C, Duclos B, Grangeasse C, Vaganay E, Riberty M, Cozzone AJ, Doublet P
(2000) J Mol Biol 304 : 311-21

19.  Crystal structures of the cellulase Cel48F in complex with inhibitors and substrates give insights into its processive action.     
Parsiegla G, Reverbel-Leroy C, Tardif C, Belaich JP, Driguez H, Haser R
(2000) Biochemistry 39 : 11238-46

18.  Functional aspects of the heme bound hemophore HasA by structural analysis of various crystal forms.     
Arnoux P, Haser R, Izadi-Pruneyre N, Lecroisey A, Czjzek M
(2000) Proteins 41 : 202-10

1999 [Top] 5
17.  Amylose chain behavior in an interacting context II. Molecular modeling of a maltopentaose fragment in the barley alpha-amylase catalytic site      
Andre G, Buleon A, Juy M, Aghajari N, Haser R, Tran V
(1999) BIOPOLYMERS  49 : 107-119

16.  Alternative procedure for two-dimensional separation of phosphoamino acids.     
Grangeasse C, Riberty M, Vaganay E, Duclos B
(1999) Biotechniques 27 : 62-4

15.  Amylose chain behavior in an interacting context. III. Complete occupancy of the AMY2 barley alpha-amylase cleft and comparison with biochemical data.     
Andre G, Buleon A, Haser R, Tran V
(1999) Biopolymers 50 : 751-62

14.  Key role of phenylalanine 20 in cytochrome c3: structure, stability, and function studies.     
Dolla A, Arnoux P, Protasevich I, Lobachov V, Brugna M, Giudici-Orticoni MT, Haser R, Czjzek M, Makarov A, Bruschi M
(1999) Biochemistry 38 : 33-41

13.  The crystal structure of HasA, a hemophore secreted by Serratia marcescens.     
Arnoux P, Haser R, Izadi N, Lecroisey A, Delepierre M, Wandersman C, Czjzek M
(1999) Nat Struct Biol 6 : 516-20

1998 [Top] 10
12.  Crystallization of the catalytic domain of Clostridium cellulolyticum CeLF cellulase in the presence of a newly synthesized cellulase inhibitor.     
Reverbel-Leroy C, Parsiegla G, Moreau V, Juy M, Tardif C, Driguez H, Belaich JP, Haser R
(1998) Acta Crystallogr D Biol Crystallogr 54 : 114-8

11.  Crystal structure of oxidized trimethylamine N-oxide reductase from Shewanella massilia at 2.5 A resolution.     
Czjzek M, Dos Santos JP, Pommier J, Giordano G, Mejean V, Haser R
(1998) J Mol Biol 284 : 435-47

10.  The crystal structure of the processive endocellulase CelF of Clostridium cellulolyticum in complex with a thiooligosaccharide inhibitor at 2.0 A resolution.     
Parsiegla G, Juy M, Reverbel-Leroy C, Tardif C, Belaich JP, Driguez H, Haser R
(1998) EMBO J 17 : 5551-62

9.  Structural and kinetic studies of the Y73E mutant of octaheme cytochrome c3 (Mr = 26 000) from Desulfovibrio desulfuricans Norway.     
Aubert C, Giudici-Orticoni MT, Czjzek M, Haser R, Bruschi M, Dolla A
(1998) Biochemistry 37 : 2120-30

8.  Crystal structures of the psychrophilic alpha-amylase from Alteromonas haloplanctis in its native form and complexed with an inhibitor.     
Aghajari N, Feller G, Gerday C, Haser R
(1998) Protein Sci 7 : 564-72

7.  Barley alpha-amylase bound to its endogenous protein inhibitor BASI: crystal structure of the complex at 1.9 A resolution.     
Vallee F, Kadziola A, Bourne Y, Juy M, Rodenburg KW, Svensson B, Haser R
(1998) Structure 6 : 649-59

6.  Functional characterization of the low-molecular-mass phosphotyrosine-protein phosphatase of Acinetobacter johnsonii.     
Grangeasse C, Doublet P, Vincent C, Vaganay E, Riberty M, Duclos B, Cozzone AJ
(1998) J Mol Biol 278 : 339-47

5.  Crystal structures of the psychrophilic alpha-amylase from Alteromonas haloplanctis in its native form and complexed with an inhibitor (vol 7, pg 565, 1998)      
Aghajari N, Feller G, Gerday C, Haser R
(1998) PROTEIN SCIENCE  7 : 1481-1481

4.  Molecular structure of a barley alpha-amylase-inhibitor complex: implications for starch binding and catalysis.     
Kadziola A, Søgaard M, Svensson B, Haser R
(1998) J Mol Biol 278 : 205-17

3.  Structures of the psychrophilic Alteromonas haloplanctis alpha-amylase give insights into cold adaptation at a molecular level.     
Aghajari N, Feller G, Gerday C, Haser R
(1998) Structure 6 : 1503-16

1997 [Top] 1
2.  Cyclic AMP stimulates the protein tyrosine kinase activity of Acinetobacter calcoaceticus      
Grangeasse C, Vaganay E, Doublet P, Riberty M, Cozzone AJ, Duclos B
(1997) FEMS MICROBIOLOGY LETTERS  152 : 333-337

1996 [Top] 1
1.  Autophosphorylation of a bacterial protein at tyrosine.     
Duclos B, Grangeasse C, Vaganay E, Riberty M, Cozzone AJ
(1996) J Mol Biol 259 : 891-5